Week 5 Fantasy Football: Top Defenses, QB Starts, and Key Waiver Targets

Week 5 Fantasy Football: Top Defenses, QB Starts, and Key Waiver Targets

As the NFL season hits its stride in Week 5, fantasy managers are scrambling to lock in their lineups amid a slew of injuries and surprise performances. The bye weeks are starting to bite, forcing tough choices on defenses and quarterbacks alike. Indeed, with several high-powered offenses facing favorable matchups, picking the right DST could make or break your week.

Defensive rankings shake up notably this time around. The Philadelphia Eagles DST tops the list, poised to exploit a shaky Giants line that's given up 12 sacks already this year. Close behind, the Denver Broncos defense emerges as a streamer gem against the Raiders, who've turned the ball over six times in their last three games. However, steer clear of the Chicago Bears unit if possible; their secondary has been porous, allowing over 250 passing yards per contest lately. Start 'em options include the Jets against a Vikings offense still finding its rhythm post-Sam Bradford, while sitting the Cardinals might save you from Patrick Mahomes' inevitable magic.

Shifting to quarterbacks, the rankings favor mobility and matchup edges. Jalen Hurts leads as a must-start, fresh off three straight games with multiple scores, facing a Washington secondary ranked 28th in pass defense. Lamar Jackson follows closely, though his rushing upside tempers any concerns against Cincy's stout front. For sleepers, consider Justin Fields if you're in a pinch—his legs could feast on the Commanders. But who should you sit? Bo Nix drops amid a brutal Falcons matchup, where their defense has clamped down on rookie QBs all season.

On the waiver wire, Darius Slayton stands out as a wideout pickup for Giants fans reeling from Malik Nabers' latest tweak—expected out another week with a hamstring pull. Slayton, who's seen 15 targets over the past two games, could see even more volume with Daniel Jones airing it out. As for Malik Washington, the Dolphins rookie has quietly notched 120 yards receiving in spot duty, but his role remains fringe until Tyreek Hill shakes off that ankle knock. Moreover, these moves highlight how injuries keep reshaping rosters faster than expected.

Yet, in the end, Week 5 reminds us that fantasy success often hinges on those overlooked decisions—what might your next lineup tweak reveal about the season ahead?

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