“Grey’s Anatomy,” the beloved American medical drama television series, has returned for its twenty-second season, captivating audiences with its compelling narrative and intricate character development. The season, which premiered on October 9, 2025, on the American Broadcasting Company (ABC), continues to be a cornerstone of medical drama. One of the standout performances in the upcoming 2026 episodes is that of Camilla Luddington as Dr. Jo Wilson, a character who has consistently proved her prowess in the operating room and beyond.
Season 22 marks a significant milestone as it is the first season without Jake Borelli and Midori Francis as series regulars since the sixteenth and nineteenth seasons, respectively. Despite these changes, the series continues to maintain its core focus on the medical dramas within Seattle’s Grey Sloan Memorial Hospital, where the staff face unprecedented challenges in the wake of a major explosion that caused extensive damage to the hospital.
In a significant turn of events, season 22 finds the hospital and its staff on a long path to recovery, adding layers of tension and emotional depth to the narrative. This season also brings new faces and familiar ones, with returning talent including Ellen Pompeo as Dr. Meredith Grey, Chandra Wilson as Dr. Miranda Bailey, James Pickens Jr. as Dr. Richard Webber, and Camilla Luddington as Dr. Jo Wilson, among others. The show has consistently showcased their exceptional performances and complex character arcs, making each episode a must-watch for fans of the series.
For those eager to catch the latest episodes, the season 22 midseason premiere occurred on January 8, 2026, on ABC, providing a thrilling continuation of the ongoing storylines. The episodes air live on Thursdays at 10/9c PM, with new episodes available for streaming on Hulu the next day after each episode airs. This scheduling allows viewers to stay up-to-date with the show whether they prefer live viewing or streaming at their convenience.
The return of “Grey’s Anatomy” season 22 has been highly anticipated, and the show continues to engage audiences with its dramatic twists, emotional depth, and exceptional performances by its cast, including the notable contributions of Camilla Luddington. As the series progresses, viewers can expect more surprises and heart-wrenching moments from the beloved characters at Grey Sloan Memorial Hospital.
