Falcons Upset 49ers 29-20 in Week 7, Ending San Francisco's Perfect Start

Falcons Stun 49ers 29-20 on October 25

Sunday, October 25, 2026, featured the Atlanta Falcons defeating the San Francisco 49ers 29-20 in a Week 7 matchup.

The game marked the 49ers' first loss after opening the season 6-0, a stretch in which quarterback Brock Purdy had thrown for 1,460 yards, 14 touchdowns and two interceptions while the offense averaged 29.5 points per game.

Pur​dy was intercepted twice; one pass intended for a receiver was abandoned near the sideline, and Jessie Bates seized the ball for an Atlanta defensive play.

Following the interception, Purdy explained that he expected Christian Kirk to be in position on the scramble but realized the receiver was not there, prompting him to attempt a throwaway.

San Francisco’s defense limited Atlanta’s star running back Bijan Robinson to 63 yards, even as the Falcons’ offense accumulated 29 points.

Injury concerns persisted for the 49ers, with Christian McCaffrey listed as having an injury scare that did not appear serious, and the team confirmed that Mike Evans, Deebo Samuel and Nick Bosa remained sidelined.

Atlanta entered the contest with a 2-4 record, led by quarterback Michael Penix Jr., and sought to capitalize on the 49ers’ defense, which had allowed just 18.3 points per game through the first six weeks.

Post‑game, the 49ers were also reported to be exploring trade interest in former San Francisco defensive tackle DeForest Buckner.